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KMID : 0880520070430020067
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Chonnam Medical Journal
2007 Volume.43 No. 2 p.67 ~ p.72
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Mesenchymal Stem Cells and Their Potential as Therapeutics in Ischemic Heart Disease
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Kim Yong-Sook
Jeong Myung-Ho
Cho Jeong-Gwan
Park Jong-Chun
Ahn Young-Keun
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Abstract
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There has been a rapid progress in research to reveal the molecular mechanism underlying therapeutic effect of mesenchymal stem cells (MSCs) on cardiovascular diseases. To maximize the beneficial potency of MSCs, various factors such as growth factors and cytokines are applied both directly and indirectly. In addition to modification of stem cell itself, safe and feasible stem cell sources including umbilical cord blood and adipose tissue are actively developed. In conclusion, modified MSCs from various adult tissue were showed beneficial and therapeutic effects on cardiovascular diseases.
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KEYWORD
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Mesenchymal stem cell, Myocardial infartion, Modification
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